Vitelliform macular dystrophy of late onset.
نویسندگان
چکیده
A family with vitelliform macular dystrophy is presented in which the proband became symptomatic at age 51 rather than during the more typical first or second decade. Elderly patients with vitelliform macular dystrophy may have clinical findings resembling age-related degenerative choroidopathy of the macula.
منابع مشابه
Adult onset Best's macular dystrophy (VMD2) with unilateral presentation.
BACKGROUND Vitelliform macular dystrophy is an autosomal-dominant disease and has two clinical variants: Best's (VMD2) and adult onset vitelliform macular dystrophy (AOVMD). We report an atypical presentation of VMD2. CASE A 50-year-old male presented with history of blurring of vision in left eye since two year. On fundus examination, left eye revealed a single, circular, yellow-opaque egg y...
متن کاملPeripherin/RDS and VMD2 mutations in macular dystrophies with adult-onset vitelliform lesion.
PURPOSE Adult-onset vitelliform macular dystrophy (AVMD) is a pleomorphic late-onset macular phenotype characterized by a central yellow deposit between the neural retina and retinal pigment epithelium. Mutations in the genes encoding peripherin/RDS and VMD2 have been previously reported in some subjects with AVMD. The purpose of this investigation was to determine the prevalence of mutations i...
متن کاملOptical coherence tomography of adult-onset vitelliform dystrophy.
PURPOSE To report the cross-sectional structure of the retina and choroid in eyes with adult-onset vitelliform macular dystrophy as obtained by optical coherence tomography (OCT). METHODS Seven patients with adult-onset vitelliform macular dystrophy and one patient with Best disease were examined by fundoscopy, fluorescein and indocyanine green angiography and OCT. Three patients underwent al...
متن کاملMorphological and functional analyses of adult onset vitelliform macular dystrophy.
AIM To evaluate the morphology and visual function of the macula in eyes with adult onset vitelliform macular dystrophy (AVMD). METHODS 12 eyes of six patients with AVMD were examined by ophthalmoscopy, scanning laser ophthalmoscopy (SLO), optical coherence tomography (OCT), and multifocal electroretinography (mfERGs). The macular lesions were bilateral in all patients and varied from the typ...
متن کاملNovel mutation in BEST1 associated with retinoschisis.
Best vitelliform macular dystrophy (BVMD) is caused by mutations in BEST1 (also known as VMD2; OMIM 153700) on the long arm of chromosome 11. An array of BEST1 phenotypes have now been characterized, including microcornea, rodcone dystrophy, early-onset catar ac t , pos t e r io r s t aphy loma syndrome, vitreoretinochoroidopathy, and adult-onset foveomacular vitelliform dystrophy. BEST1 encode...
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ورودعنوان ژورنال:
- The British journal of ophthalmology
دوره 65 12 شماره
صفحات -
تاریخ انتشار 1981